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Possible Blood Types

It is usually not recommended to limit your donor search by trying to match a donor’s blood type to your own.  But, for some intended parents especially those who come from certain cultures or religions this is an important factor for personal reasons not for medical reasons.  Medically blood type is not important in third party reproduction.

There are four basic blood types, O, A, B, and AB.  With O being the most common and AB being the least common. We all inherit one allele from each of our parents.  There are three basic blood type alleles, A, B, andO. 
Possible allele combinations are:
                                                OO
                                                AO
                                                BO
                                                AB
                                                AA
                                                BB

Blood types A and B are called codominant alleles; blood type O is a recessive allele.  A codominant allele is apparent even if only one is present a recessive allele is apparent only if two recessive alleles are present.  Therefore, since O blood type is recessive, it is not apparent if the person inherits an A or B allele along with it.

Possible allele combinations result in a particular blood type as follows:

                                               OO = blood type O
                                               AO = blood type A
                                               BO = blood type B
                                               AB = blood type AB
                                               AA = blood type A
                                               BB = blood type B

You can see that a person with blood type B may have a B and an O allele, or they may have two B alleles. If both parents are blood type B and both have a B and a recessive O, then their children will either be BB (if each parent passed on the B allele), BO (if one parent passed on B and the other parent passed on O), or OO (if both parents passed on the O allele). If the child is BB or BO, they have blood type B. If the child is OO, he or she will have blood type O.

Therefore, you can see that it is not at all unusual for two parents with blood type B (or blood type A) to have children with blood type O blood.
 
 

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